苯扎氯铵杂质2

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 0.5 mol of dimethyl-cetylamine known under the trademark "Armeen DM 16D" is heated at 90°-95° C. for 11/2 hours with 0.5 mol of ethyl monochloroacetate and 40 g of absolute alcohol. Carboethoxymethyl-dimethyl-cetyl -ammonium chloride is obtained.

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:50.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In a 100 ml flask commercial vinylbenzyl chloride (3.05 g, 0.020 mol) was mixed with hexadecyldimethylamine (5.4 g, 0.020 mol) without any additional solvent. After addition of 2,6-di-tert-butyl-4-methylphenol (100 mg, 0.45 mmol) the mixture was heated overnight at 50° C. The solid product which formed was washed several times with dry ether, dried under vacuum at room temperature, and recrystallized from acetone/ether to give 6.3 g (75%) of 4-styrylmethyl (hexadecyl)dimethylammonium chloride. 1H NMR (CDCl3 /Me4Si): 0.88 (s, 3H), 1.24 (br s, 26H ), 1.78 (s, 2H), 3.30 (s, 6H), 3.53 (s, 2H), 5.08 (s, 2H), 5.32 (d, J=10.8Hz, 1H), 5.84(d, J=18Hz, 1H), 6.7 (m, 1H), 7.51 (m, 4H). IR (KBr); 3020, 2920, 1640 cm-1. The critical micelle concentration (CMC) was 1.28× 10-2M at 25° C. determined conductometrically. The solid product which formed was washed several times with dry ether dried under vacuum at room temperature recrystallized from acetone/ether

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 16.8 grams of allyl iodide were dissolved in 44.6 grams of ethyl acetate and 27.8 grams of dimethyl hexadecyl amine were added slowly with stirring at room temperature. Within 15 minutes after the addition of the amine was complete, the viscosity of the solution increased and crystallization occurred. After 24 hours the crystals were filtered, washed with ethyl acetate, and dried. The colorless crystalline product contained 88% of the theoretical amount of iodide ion. the viscosity of the solution increased crystallization After 24 hours the crystals were filtered washed with ethyl acetate dried

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Allyl hexadecyl dimethyl ammonium chloride was prepared by reacting allyl chloride and dimethyl hexadecyl amine as set forth in Example 1. 17.8 grams of the chloride in 23.5% aqueous solution were treated with a stoichiometric excess of AgF in aqueous solution until analysis of the filtrate showed only a trace of chloride ion present. Excess silver ion was removed by the careful addition of NaCl, AgCl being removed by filtration. Excess silver ion was removed by the careful addition of NaCl, AgCl being removed by filtration

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 16.8 grams of allyl iodide were dissolved in 44.6 grams of ethyl acetate and 27.8 grams of dimethyl hexadecyl amine were added slowly with stirring at room temperature. Within 15 minutes after the addition of the amine was complete, the viscosity of the solution increased and crystallization occurred. After 24 hours the crystals were filtered, washed with ethyl acetate, and dried. The colorless crystalline product contained 88% of the theoretical amount of iodide ion. the viscosity of the solution increased crystallization After 24 hours the crystals were filtered washed with ethyl acetate dried

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Allyl hexadecyl dimethyl ammonium chloride was prepared by reacting allyl chloride and dimethyl hexadecyl amine as set forth in Example 1. 17.8 grams of the chloride in 23.5% aqueous solution were treated with a stoichiometric excess of AgF in aqueous solution until analysis of the filtrate showed only a trace of chloride ion present. Excess silver ion was removed by the careful addition of NaCl, AgCl being removed by filtration. Excess silver ion was removed by the careful addition of NaCl, AgCl being removed by filtration

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 0.5 mol of dimethyl-cetylamine known under the trademark "Armeen DM 16D" is heated at 90°-95° C. for 11/2 hours with 0.5 mol of ethyl monochloroacetate and 40 g of absolute alcohol. Carboethoxymethyl-dimethyl-cetyl -ammonium chloride is obtained.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 0.5 mol of dimethyl-cetylamine known under the trademark "Armeen DM 16D" is heated at 90°-95° C. for 11/2 hours with 0.5 mol of ethyl monochloroacetate and 40 g of absolute alcohol. Carboethoxymethyl-dimethyl-cetyl -ammonium chloride is obtained.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A mixture of hexadecyldimethylamine (0.1 mol) and phenacyl bromide (0.1 mol) in ethanol was refluxed for 5 hours. Ethanol was removed under reduced pressure and the product was crystallised from acetone. was refluxed for 5 hours Ethanol was removed under reduced pressure the product was crystallised from acetone