(2S)-N-苄基吡咯烷-2-甲酰胺

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 413 g of the proline benzylamide obtained in this way were dissolved in 400 ml of isopropanol. 630 ml of a saturated solution of HCl in isopropanol were added, the resulting suspension was stirred at 0°-5° C. for 2 h, and the solid was filtered off with suction and washed twice with 250 ml of isopropanol. The residue was dried at 50° C. under reduced pressure to obtain 401 g of proline benzylamide hydrochloride; aD20 :--45° the solid was filtered off with suction washed twice with 250 ml of isopropanol The residue was dried at 50° C. under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 413 g of the proline benzylamide obtained in this way were dissolved in 400 ml of isopropanol. 630 ml of a saturated solution of HCl in isopropanol were added, the resulting suspension was stirred at 0°-5° C. for 2 h, and the solid was filtered off with suction and washed twice with 250 ml of isopropanol. The residue was dried at 50° C. under reduced pressure to obtain 401 g of proline benzylamide hydrochloride; aD20 :--45° the solid was filtered off with suction washed twice with 250 ml of isopropanol The residue was dried at 50° C. under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 413 g of the proline benzylamide obtained in this way were dissolved in 400 ml of isopropanol. 630 ml of a saturated solution of HCl in isopropanol were added, the resulting suspension was stirred at 0°-5° C. for 2 h, and the solid was filtered off with suction and washed twice with 250 ml of isopropanol. The residue was dried at 50° C. under reduced pressure to obtain 401 g of proline benzylamide hydrochloride; aD20 :--45° the solid was filtered off with suction washed twice with 250 ml of isopropanol The residue was dried at 50° C. under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 413 g of the proline benzylamide obtained in this way were dissolved in 400 ml of isopropanol. 630 ml of a saturated solution of HCl in isopropanol were added, the resulting suspension was stirred at 0°-5° C. for 2 h, and the solid was filtered off with suction and washed twice with 250 ml of isopropanol. The residue was dried at 50° C. under reduced pressure to obtain 401 g of proline benzylamide hydrochloride; aD20 :--45° the solid was filtered off with suction washed twice with 250 ml of isopropanol The residue was dried at 50° C. under reduced pressure