1H-Azepine-4-carboxylic acid, hexahydro-, methyl ester

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound is prepared according to the reaction sequence 2.001a-2.001d described above using 5-methylnicotinoyl chloride instead of 4-chlorobenzoyl chloride as in 2.001a and rac-methyl azepane-4-carboxylate instead of ethyl isonipecotate as in 2.001c: LC-MS A: tR=0.48 min; [M+H]+=368.14.