4-(2,4-二氯苯基)-3,4-二氢-2H-萘-1-one

反应条件: temp:65.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In a suspension of 60 g (0.45 mole) of aluminium chloride in 100 ml of metadichlorobenzene, 28.8 g (0.2 mole) of α-naphthol are introduced in 10 minutes: the temperature rises from 20° to 45° C. The medium is heated for 1 hour 30 mins at 65° C. then hydrolysed with 400 ml of water. After decantation, the organic phase is separated and concentrated in a vacuum from 2 to 5 torrs at 80° C. The residue is dissolved in 100 ml of isopropanol and the resultant solution cooled at 0° C. for 2 hours. The light beige solid formed is separated by filtration and dried to obtain 41.5 g of the expected compound. are introduced in 10 minutes rises from 20° to 45° C After decantation, the organic phase is separated concentrated in a vacuum from 2 to 5 torrs at 80° C The residue is dissolved in 100 ml of isopropanol the resultant solution cooled at 0° C. for 2 hours The light beige solid formed is separated by filtration dried