3,4-BIS(HYDROXYMETHYL)FURAN

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: According to a similar procedure to that described in Example 21-(2), 3,4-furandimethanol (described in J. Org. Chem., 65, 6153 (2000); 3.4 g, 26.5 mmol) was reacted with imidazole (1.80 g, 26.4 mmol) and tert-butylchlorodimethylsilane (4.00 g, 26.5 mmol) in tetrahydrofuran (50 ml), and the reaction mixture was worked up to afford a mixture of the title compound, 3,4-furandimethanol and 3,4-bis[(tert-butyldimethylsilyl)oxymethyl]furan. The mixture was subjected to chromatography on a silica gel (50 g) column (eluent; ethyl acetate:hexane=3:17˜4:16) to afford the title compound (3.20 g, 50% yield) as a colorless oil. to afford