N-(环丙基亚甲基)羟胺

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Following a procedure similar to that described in Example 2(b) and using 0.52 g N-chlorosuccinimide in 5 mls dimethylformamide, two drops of pyridine, 0.33 g cyclopropanecarboxaldehyde oxime from part (a) above in 10 mls dimethylformamide, 0.53 g 3-[3,5-dimethyl-4-(3-ethinylpropoxy)phenyl]-5-methyl-1,2,4-oxadiazole prepared by a procedure similar to that described in Example 1(b), and 0.40 g triethylamine in 20 mls dimethylformamide, there was obtained after chroamtography (MPLC, silica gel; 20:80 ethyl acetate/hexane) and recrystallization (methyl alcohol) 0.312 g of the title compound, m.p. 50.5°-51° C. prepared by a procedure similar to there was obtained after chroamtography (MPLC, silica gel; 20:80 ethyl acetate/hexane) and recrystallization (methyl alcohol) 0.312 g of the title compound, m.p. 50.5°-51° C.