[4-(氨基甲基)苯基]甲磺酰胺

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[4-(Aminosulphonylmethyl)benzyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(aminomethyl)benzylsulphonamide using method H. NMR; δH [2H6]—DMSO 9.17,(1H, t), 8.00,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.56-7.51,(3H, m), 7.33,(4H, m), 6.82,(2H, b), 4.50,(2H, d), 4.23,(2H, s), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 2.90 min, MH+ 477.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[4-(Aminosulphonylmethyl)benzyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(aminomethyl)benzylsulphonamide using method H. NMR; δH [2H6]—DMSO 9.17,(1H, t), 8.00,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.56-7.51,(3H, m), 7.33,(4H, m), 6.82,(2H, b), 4.50,(2H, d), 4.23,(2H, s), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 2.90 min, MH+ 477.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[4-(Aminosulphonylmethyl)benzyl]-2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxylic acid and 4-(aminomethyl)benzylsulphonamide using method H. NMR; δH [2H6]—DMSO 9.17,(1H, t), 8.00,(2H, d), 7.89,(1H, dd), 7.76,(1H, d), 7.56-7.51,(3H, m), 7.33,(4H, m), 6.82,(2H, b), 4.50,(2H, d), 4.23,(2H, s), 2.56,(3H, s), 2.31,(3H, s). LCMS; retention time 2.90 min, MH+ 477.