5H-二苯并[B,F]氮杂环庚烯-10(11H)-酮

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 22.3 g of 10-methoxy-5H-dibenz(b,f)azepine are heated under reflux with 100 ml of 2N hydrochloric acid for 2 hours. The gummy residue is extracted with chloroform (50÷50 ml), the combined extracts are washed with water and evaporated to dryness under vacuum. The residue is taken up into 200 ml of ethanol, treated with charcoal (2 g) for 1 h under reflux, filtered, evaporated to dryness under vacuum, finally taken up into 50÷50 ml of toluene, stripping thoroughly. The residue is kept for further working-up. The gummy residue is extracted with chloroform (50÷50 ml) the combined extracts are washed with water evaporated to dryness under vacuum treated with charcoal (2 g) for 1 h under reflux filtered evaporated to dryness under vacuum