4-甲硫基丁酸乙酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of ethyl 4-bromobutyrate (0.269) in N,N-dimethylformamide (3 ml) was treated with sodium thiomethoxide (0.103 g), and the mixture stirred at room temperature overnight. The mixture was partitioned between water (10ml) and dichloromethane (10 ml), and the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml). The organic layers were evaporated in vacuo to give the title compound as a clear oil (0.135 g). The mixture was partitioned between water (10ml) and dichloromethane (10 ml) the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml) The organic layers were evaporated in vacuo

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of ethyl 4-bromobutyrate (0.269) in N,N-dimethylformamide (3 ml) was treated with sodium thiomethoxide (0.103 g), and the mixture stirred at room temperature overnight. The mixture was partitioned between water (10ml) and dichloromethane (10 ml), and the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml). The organic layers were evaporated in vacuo to give the title compound as a clear oil (0.135 g). The mixture was partitioned between water (10ml) and dichloromethane (10 ml) the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml) The organic layers were evaporated in vacuo

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of ethyl 4-bromobutyrate (0.26 g) in N,N-dimethylformamide (3 ml) was treated with sodium thiomethoxide (0.103 g), and the mixture stirred at room temperature overnight. The mixture was partitioned between water (10 ml) and dichloromethane (10 ml), and the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml). The organic layers were evaporated in vacuo to give the title compound as a clear oil (0.135 g). NMR (CDCl3) 4.06δ(2H, q, CH2), 2.46δ(2H, t, CH2), 2.35δ(2H, t, CH2), 2.03δ(3H, s, CH3), 1.85δ(2H, m, CH2), 1.18δ(3H, t, CH3). The mixture was partitioned between water (10 ml) and dichloromethane (10 ml) the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml) The organic layers were evaporated in vacuo

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of ethyl 4-bromobutyrate (0.26 g) in N,N-dimethylformamide (3 ml) was treated with sodium thiomethoxide (0.103 g), and the mixture stirred at room temperature overnight. The mixture was partitioned between water (10 ml) and dichloromethane (10 ml), and the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml). The organic layers were evaporated in vacuo to give the title compound as a clear oil (0.135 g). NMR (CDCl3) 4.06δ(2H, q, CH2), 2.46δ(2H, t, CH2), 2.35δ(2H, t, CH2), 2.03δ(3H, s, CH3), 1.85δ(2H, m, CH2), 1.18δ(3H, t, CH3). The mixture was partitioned between water (10 ml) and dichloromethane (10 ml) the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml) The organic layers were evaporated in vacuo

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of ethyl 4-bromobutyrate (0.269) in N,N-dimethylformamide (3 ml) was treated with sodium thiomethoxide (0.103 g), and the mixture stirred at room temperature overnight. The mixture was partitioned between water (10ml) and dichloromethane (10 ml), and the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml). The organic layers were evaporated in vacuo to give the title compound as a clear oil (0.135 g). The mixture was partitioned between water (10ml) and dichloromethane (10 ml) the organic layer was washed with 1:1 saturated aqueous sodium chloride and water (10 ml) The organic layers were evaporated in vacuo