5-丁基噁唑-2,4-二酮

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of the starting material 2-hydroxyhexanoic acid amide was 1.3 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 25.9 mass % in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 93.8% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 88.7%. A part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of the starting material 2-hydroxyhexanoic acid amide was 1.6 mass % in the solution, the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 24.0 mass % in the solution and the concentration of 2-hydroxyhexanoic acid was 2.3 mass % in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 92.6% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 82.1%. A part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To this solution, dimethyl carbonate (74 g, 0.82 mol) and 30% sodium methylate (147 g, 0.82 mol) were again added and reacted at from 60 to 70° C. for 2 hours. Thereafter, a part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of 2 -hydroxyhexanoic acid amide was 0 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 27.5% in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 100% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 94.1%. reacted at from 60 to 70° C. for 2 hours Thereafter, a part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To this solution, dimethyl carbonate (74 g, 0.82 mol) and 30% sodium methylate (147 g, 0.82 mol) were again added and reacted at from 60 to 70° C. for 2 hours. Thereafter, a part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of 2 -hydroxyhexanoic acid amide was 0 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 27.5% in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 100% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 94.1%. reacted at from 60 to 70° C. for 2 hours Thereafter, a part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of the starting material 2-hydroxyhexanoic acid amide was 1.3 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 25.9 mass % in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 93.8% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 88.7%. A part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of the starting material 2-hydroxyhexanoic acid amide was 1.6 mass % in the solution, the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 24.0 mass % in the solution and the concentration of 2-hydroxyhexanoic acid was 2.3 mass % in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 92.6% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 82.1%. A part of the reaction solution was sampled

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To this solution, dimethyl carbonate (74 g, 0.82 mol) and 30% sodium methylate (147 g, 0.82 mol) were again added and reacted at from 60 to 70° C. for 2 hours. Thereafter, a part of the reaction solution was sampled and the components of the reaction solution were analyzed by HPLC, as a result, the concentration of 2 -hydroxyhexanoic acid amide was 0 mass % in the solution and the concentration of 5-butyl-oxazolidin-2,4-dione sodium salt as the objective product was 27.5% in the solution. From these analysis values, the conversion of 2-hydroxyhexanoic acid amide was 100% and the yield in terms of 5-butyl-oxazolidin-2,4-dione was 94.1%. reacted at from 60 to 70° C. for 2 hours Thereafter, a part of the reaction solution was sampled