4-戊基哌啶

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 5 g of 1-(4-methoxycarbonylcyclohexen-1-yl)-4-pentylpiperidine (b.p. 171°/0.4 mm Hg, obtainable from methyl cyclohexanone-4-carboxylate and 4-pentylpiperidine in toluene in the presence of p-toluenesulfonic acid) in 50 ml of THF is hydrogenated under 2 bar of H2 using 0.5 g of 10% Pd-C; the catalyst is filtered off; and the filtrate is evaporated to dryness to give 1-(trans-4-methoxycarbonylcyclohexyl)4-pentylpiperidine, m.p. 5°, b.p. 177°/0.27 mbar. the catalyst is filtered off and the filtrate is evaporated to dryness

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 5 g of 1-(4-methoxycarbonylcyclohexen-1-yl)-4-pentylpiperidine (b.p. 171°/0.4 mm Hg, obtainable from methyl cyclohexanone-4-carboxylate and 4-pentylpiperidine in toluene in the presence of p-toluenesulfonic acid) in 50 ml of THF is hydrogenated under 2 bar of H2 using 0.5 g of 10% Pd-C; the catalyst is filtered off; and the filtrate is evaporated to dryness to give 1-(trans-4-methoxycarbonylcyclohexyl)4-pentylpiperidine, m.p. 5°, b.p. 177°/0.27 mbar. the catalyst is filtered off and the filtrate is evaporated to dryness

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 5 g of 1-(4-methoxycarbonylcyclohexen-1-yl)-4-pentylpiperidine (b.p. 171°/0.4 mm Hg, obtainable from methyl cyclohexanone-4-carboxylate and 4-pentylpiperidine in toluene in the presence of p-toluenesulfonic acid) in 50 ml of THF is hydrogenated under 2 bar of H2 using 0.5 g of 10% Pd-C; the catalyst is filtered off; and the filtrate is evaporated to dryness to give 1-(trans-4-methoxycarbonylcyclohexyl)4-pentylpiperidine, m.p. 5°, b.p. 177°/0.27 mbar. the catalyst is filtered off and the filtrate is evaporated to dryness