[1,4]DIOXAN-2-YLMETHYL-METHYL-AMINE

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-bromo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride with (±)-N-methyl-N-(1,4-dioxan-2-ylmethyl)amine, the title compound was obtained. Proton NMR for the product was consistent with the titled compound. ESI+ MS: 432.2 [M+H]+.