3-羟基丙酰胺

反应条件: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 82 g of β-hydroxypropionamide and 195 g of dodecylamine were heated with 50 mg of 2,6-di-t-butyl-p-cresol for 4 hours in a temperature range of 130° C. to 190° C. unitl the evolution of ammonia was complete. After adding 5 g of polyphosphoric acid the reaction mixture was maintained at 160° C. for 1 hour and then distilled in an oil pump vacuum. The main run was taken off between 148° C. and 168° C. at 0.3 bar and crystallized in the receiver. distilled in an oil pump vacuum was taken off between 148° C. and 168° C. at 0.3 bar crystallized in the receiver

反应条件: temp:164.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 59 g of β-hydroxypropionamide and 69.4 g of cyclohexylamine were heated with 50 mg of 2,6-di-t-butyl-pcresol for 5 hours in a temperature range of 130°-170° C. until the evolution of ammonia was complete. After adding 2.5 g of polyphosphoric acid the reaction mixture was maintained at 164° C. for 1 hour and then distilled in a water jet vacuum. The main run was taken off between 140° and 160° C. at 11 bar and crystallized in the receiver. distilled in a water jet vacuum was taken off between 140° and 160° C. at 11 bar crystallized in the receiver

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 59 g of β-hydroxypropionamide and 75 g of benzylamine were heated with 50 mg of 2,6-di-t-butyl-p-cresol for 7 hours in a temperature range of 120°-170° C. until the evolution of ammonia was complete. After adding 2.2 g of polyphosphoric acid distillation was carried out in an oil pump vacuum; the subsequent redistillation with the addition of 1 ml of sulphuric acid yielded 92 g of N-benzylacrylamide, Bp0.1 113° C., which crystallized in the receiver. Mp (crude product): 53° C. After adding 2.2 g of polyphosphoric acid distillation the subsequent redistillation with the addition of 1 ml of sulphuric acid

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 59.3 g of β-hydroxypropionic acid amide and 68 g of 3-dimethylaminopropylamine were heated for 5 hours in a temperature range of 125°-168° C. until the evolution of ammonia was complete. After adding 1 g of pulverised sodium hydroxide the reaction mixture was distilled. was distilled