2,2-二甲基-1,3-二氧环戊烷

反应条件: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: tert-Butyl lithium (2 eq) is added to a solution of (S)-4-(1-iodocyclopropyl)methyl)-2,2-dimethyl-1,3-dioxolane (1 eq) in ether at −78° C. and the mixture stirred at −78° C. for 30 mins. A solution of thionyl chloride in ether is added, the mixture warmed to room temperature and concentrated under reduced pressure. The residue is dissolved in chloroform, filtered and dried under reduced pressure. the mixture warmed to room temperature concentrated under reduced pressure The residue is dissolved in chloroform filtered dried under reduced pressure

反应条件: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: tert-Butyl lithium (2 eq) is added to a solution of (S)-4-(1-iodocyclopropyl)methyl)-2,2-dimethyl-1,3-dioxolane (1 eq) in ether at −78° C. and the mixture stirred at −78° C. for 30 mins. A solution of thionyl chloride in ether is added, the mixture warmed to room temperature and concentrated under reduced pressure. The residue is dissolved in chloroform, filtered and dried under reduced pressure. the mixture warmed to room temperature concentrated under reduced pressure The residue is dissolved in chloroform filtered dried under reduced pressure

反应条件: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: tert-Butyl lithium (2 eq) is added to a solution of (S)-4-(1-iodocyclopropyl)methyl)-2,2-dimethyl-1,3-dioxolane (1 eq) in ether at −78° C. and the mixture stirred at −78° C. for 30 mins. A solution of thionyl chloride in ether is added, the mixture warmed to room temperature and concentrated under reduced pressure. The residue is dissolved in chloroform, filtered and dried under reduced pressure. the mixture warmed to room temperature concentrated under reduced pressure The residue is dissolved in chloroform filtered dried under reduced pressure

反应条件: temp:75.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Example 1 was prepared by combining 2,2-dimethyl-1,3-dioxolane (200 g, 1.96 moles, Fluka Chemie GmbH, Deisenhofen, Germany) and Luperox 575 (10 g, 0.041 moles) (Arkema, Oakville, Ontario, Canada) were combined in a 600 mL Parr reactor (Parr Instrument Co., Moline, Ill.). The reactor was warmed to 75° C. and hexafluoropropene (300 g, 2.0 moles) (MDA Manufacturing Inc., Decatur, Ala.) was added at a constant rate. The reactor was allowed to stir at this temperature for 16 h. The crude reaction material was distilled using a ten plate Oldershaw column to afford 4-(1,1,2,3,3,3-hexafluoropropyl)-1,3-dioxolane (boiling point (b.p.) of 144° C.). Example 1 was prepared The crude reaction material was distilled

反应条件: temp:75.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Example 1 was prepared by combining 2,2-dimethyl-1,3-dioxolane (200 g, 1.96 moles, Fluka Chemie GmbH, Deisenhofen, Germany) and Luperox 575 (10 g, 0.041 moles) (Arkema, Oakville, Ontario, Canada) were combined in a 600 mL Parr reactor (Parr Instrument Co., Moline, Ill.). The reactor was warmed to 75° C. and hexafluoropropene (300 g, 2.0 moles) (MDA Manufacturing Inc., Decatur, Ala.) was added at a constant rate. The reactor was allowed to stir at this temperature for 16 h. The crude reaction material was distilled using a ten plate Oldershaw column to afford 4-(1,1,2,3,3,3-hexafluoropropyl)-1,3-dioxolane (boiling point (b.p.) of 144° C.). Example 1 was prepared The crude reaction material was distilled

反应条件: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: tert-Butyl lithium (2 eq) is added to a solution of (S)-4-(1-iodocyclopropyl)methyl)-2,2-dimethyl-1,3-dioxolane (1 eq) in ether at −78° C. and the mixture stirred at −78° C. for 30 mins. A solution of thionyl chloride in ether is added, the mixture warmed to room temperature and concentrated under reduced pressure. The residue is dissolved in chloroform, filtered and dried under reduced pressure. the mixture warmed to room temperature concentrated under reduced pressure The residue is dissolved in chloroform filtered dried under reduced pressure