羟丁基三甲基硅烷

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 439 mg (3 mmol) of 4-(Trimethylsilyl)butan-1-ol and 901 mg (3 mmol) of 4-(5-n-octyloxypyrimidin-2-yl)phenol are added to the solution of 0.46 ml (3 mmol) of diethyl azodicarboxylate and 790 mg (3 mmol) of triphenylphosphine in 15 ml of dry tetrahydrofuran. After a reaction time of 15 h, the solvent is distilled off and the residue is purified chromatographically (SiO2 /CH2Cl2). After recrystallization from n-hexane, 790 mg of colorless crystals are obtained. After a reaction time of 15 h, the solvent is distilled off the residue is purified chromatographically (SiO2 /CH2Cl2) After recrystallization from n-hexane, 790 mg of colorless crystals are obtained

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 439 mg (3 mmol) of 4-(Trimethylsilyl)butan-1-ol and 901 mg (3 mmol) of 4-(5-n-octyloxypyrimidin-2-yl)phenol are added to the solution of 0.46 ml (3 mmol) of diethyl azodicarboxylate and 790 mg (3 mmol) of triphenylphosphine in 15 ml of dry tetrahydrofuran. After a reaction time of 15 h, the solvent is distilled off and the residue is purified chromatographically (SiO2 /CH2Cl2). After recrystallization from n-hexane, 790 mg of colorless crystals are obtained. After a reaction time of 15 h, the solvent is distilled off the residue is purified chromatographically (SiO2 /CH2Cl2) After recrystallization from n-hexane, 790 mg of colorless crystals are obtained

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 1.5 ml (11.4 mmol) of a 1 molar solution of borane dimethylsulfide was added to a cooled (0° C.) solution of 0.61 g (3.8 mmol) of 4-(trimethylsilyl)-butanoic acid in 20 ml of dry tetrahydrofuran. After work-up using the standard procedure (methanol, tetramethylethylene diamine) and flash chromatography purification on silica gel eluted with a 9:1 mixture of hexane and ethyl acetate, 0.4 g of 4-(trimethylsilyl)-1-butanol was obtained as a colorless liquid. the standard procedure (methanol, tetramethylethylene diamine) and flash chromatography purification on silica gel eluted with a 9:1 mixture of hexane and ethyl acetate

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 1.5 ml (11.4 mmol) of a 1 molar solution of borane dimethylsulfide was added to a cooled (0° C.) solution of 0.61 g (3.8 mmol) of 4-(trimethylsilyl)-butanoic acid in 20 ml of dry tetrahydrofuran. After work-up using the standard procedure (methanol, tetramethylethylene diamine) and flash chromatography purification on silica gel eluted with a 9:1 mixture of hexane and ethyl acetate, 0.4 g of 4-(trimethylsilyl)-1-butanol was obtained as a colorless liquid. the standard procedure (methanol, tetramethylethylene diamine) and flash chromatography purification on silica gel eluted with a 9:1 mixture of hexane and ethyl acetate