(2S,3S)-3-氨基-1,1,1-三氟-4-甲基戊烷-2-醇

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[(1S,2S)-3,3,3,-trifluoro-2-hydroxy-1-(isopropyl)propyl]-carbamic acid benzyl ester (740 g, 2.42 mol) obtained in Example 5 was dissolved in ethyl acetate (1500 ml), and thereto was added 20% palladium hydroxide (30 g), and the mixture was stirred at room temperature for 7 hours under hydrogen atmosphere. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to give the desired compound (420 g, yield:quantitative) as an oil. The catalyst was removed by filtration the filtrate was concentrated under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[(1S,2S)-3,3,3,-trifluoro-2-hydroxy-1-(isopropyl)propyl]-carbamic acid benzyl ester (740 g, 2.42 mol) obtained in Example 5 was dissolved in ethyl acetate (1500 ml), and thereto was added 20% palladium hydroxide (30 g), and the mixture was stirred at room temperature for 7 hours under hydrogen atmosphere. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to give the desired compound (420 g, yield:quantitative) as an oil. The catalyst was removed by filtration the filtrate was concentrated under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: N-[(1S,2S)-3,3,3,-trifluoro-2-hydroxy-1-(isopropyl)propyl]-carbamic acid benzyl ester (740 g, 2.42 mol) obtained in Example 5 was dissolved in ethyl acetate (1500 ml), and thereto was added 20% palladium hydroxide (30 g), and the mixture was stirred at room temperature for 7 hours under hydrogen atmosphere. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to give the desired compound (420 g, yield:quantitative) as an oil. The catalyst was removed by filtration the filtrate was concentrated under reduced pressure