二异丙基硫酸酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In the same manner as in Reference Example 56, ethyl 6-ethyl-1-methyl-3-(1-methylethoxy)-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (291 mg, 46%) was obtained as a pale-purple powder from the compound of Reference Example 40 (574 mg, 1.50 mmol), potassium carbonate (1.04 g, 7.5 mmol) and diisopropyl sulfate (1.37 g, 7.5 mmol). The title compound (242 mg, 97%) was obtained as a colorless powder from the thus-obtained ethyl 6-ethyl-1-methyl-3-(1-methylethoxy)-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (267 mg, 0.63 mmol) by a method similar to that in Reference Example 59.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In the same manner as in Reference Example 56, ethyl 6-ethyl-1-methyl-3-(1-methylethoxy)-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (291 mg, 46%) was obtained as a pale-purple powder from the compound of Reference Example 40 (574 mg, 1.50 mmol), potassium carbonate (1.04 g, 7.5 mmol) and diisopropyl sulfate (1.37 g, 7.5 mmol). The title compound (242 mg, 97%) was obtained as a colorless powder from the thus-obtained ethyl 6-ethyl-1-methyl-3-(1-methylethoxy)-4-oxo-5-(2-oxo-2-phenylethyl)-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-2-carboxylate (267 mg, 0.63 mmol) by a method similar to that in Reference Example 59.