2-(2-chloro-4-fluorophenyl)-N'-hydroxyethanimidamide

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 69 mg (0.20 mmol) of 5-(4-ethylphenyl)-1-(morpholin-4-ylcarbonyl)piperidine-3-carboxylic acid (Example 38A) and 45 mg (0.22 mmol, 1.1 eq.) of 2-(2-chloro-4-fluorophenyl)-N′-hydroxyethanimidamide were reacted according to the General Method 1. Yield: 59 mg (57% of theory)