2-butoxyphenol

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The compound was prepared as described in Example 1, using sodium (2.3 g, 100 mmole), o-butoxyphenol (8.30 g, 50 mmole) and piperidinoethylchloride hydrochloride (9.2 g, 50 mmole) in 150 ml of ethanol. Yield 4.4 g (32%) of product boiling at 121° C under a pressure of 0.02 mm Hg; nD25 1.5135. The compound was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To 750 ml of absolute ethanol was added gradually 13.8 g (0.60 mole) of metallic sodium cut into pieces. After all the sodium had reacted 49.8 g (0.30 mole) of o-butoxyphenol was added. The solution was cooled down in ice-water whereupon a solution of 60.0 g (0.30 mole) of diisopropylaminoethylchloride hydrochloride in 150 ml of absolute ethanol was added rapidly with stirring. The reaction mixture was then boiled under reflux for 5 hours. was added was added rapidly under reflux for 5 hours

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The compound was prepared as described in Example 1, using sodium (2.3 g, 100 mmole), o-butoxyphenol (8.30 g, 50 mmole) and piperidinoethylchloride hydrochloride (9.2 g, 50 mmole) in 150 ml of ethanol. Yield 4.4 g (32%) of product boiling at 121° C under a pressure of 0.02 mm Hg; nD25 1.5135. The compound was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To 750 ml of absolute ethanol was added gradually 13.8 g (0.60 mole) of metallic sodium cut into pieces. After all the sodium had reacted 49.8 g (0.30 mole) of o-butoxyphenol was added. The solution was cooled down in ice-water whereupon a solution of 60.0 g (0.30 mole) of diisopropylaminoethylchloride hydrochloride in 150 ml of absolute ethanol was added rapidly with stirring. The reaction mixture was then boiled under reflux for 5 hours. was added was added rapidly under reflux for 5 hours