富马酸沃诺拉赞杂质96

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis

反应条件: temp:22.01; pressure:0.00; stir:

实验步骤: 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN 4 uL mixture of each reacted solution was collected and diluted with 36 uL ACN chiral resolving regent (150 mM in DCM, 40 uL) CuI with DIPEA (400 mM in ACN) 40 uL internal standard 1-phenylprop-2-yn-1-ol (4) (25 mM in ACN) 40 uL After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate After the reaction, 10 uL of supernatant for each reaction was transferred to another 96-well plate and diluted with 190 uL ACN before the IM-MS analysis