2-(hexylamino)acetic acid

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Into an autoclave, 5.6 gr (0.03 mol) of ethyl ester of 2-(n-hexylamino)acetic acid, 15 ml (0.1125 mol) of n-hexylamine and 1 mml of ethanol were added. The mixture was heated to 120° for 40 hours. The solvent and excess amine were then evaporated. The residue was solidified in pentene at low temperature (-80° C.), recrystallized three times from hexane, then dissolved in ether and added with a saturated HCl solution in ether till acid pH. The hydrochloride was recrystallized from isopropanol. The mixture was heated to 120° for 40 hours The solvent and excess amine were then evaporated was solidified in pentene at low temperature (-80° C.) recrystallized three times from hexane dissolved in ether added with a saturated HCl solution in ether till acid pH The hydrochloride was recrystallized from isopropanol

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Into an autoclave, 5.6 gr (0.03 mol) of ethyl ester of 2-(n-hexylamino)acetic acid, 15 ml (0.1125 mol) of n-hexylamine and 1 mml of ethanol were added. The mixture was heated to 120° for 40 hours. The solvent and excess amine were then evaporated. The residue was solidified in pentene at low temperature (-80° C.), recrystallized three times from hexane, then dissolved in ether and added with a saturated HCl solution in ether till acid pH. The hydrochloride was recrystallized from isopropanol. The mixture was heated to 120° for 40 hours The solvent and excess amine were then evaporated was solidified in pentene at low temperature (-80° C.) recrystallized three times from hexane dissolved in ether added with a saturated HCl solution in ether till acid pH The hydrochloride was recrystallized from isopropanol

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Into an autoclave, 5.6 gr (0.03 mol) of ethyl ester of 2-(n-hexylamino)acetic acid, 15 ml (0.1125 mol) of n-hexylamine and 1 mml of ethanol were added. The mixture was heated to 120° for 40 hours. The solvent and excess amine were then evaporated. The residue was solidified in pentene at low temperature (-80° C.), recrystallized three times from hexane, then dissolved in ether and added with a saturated HCl solution in ether till acid pH. The hydrochloride was recrystallized from isopropanol. The mixture was heated to 120° for 40 hours The solvent and excess amine were then evaporated was solidified in pentene at low temperature (-80° C.) recrystallized three times from hexane dissolved in ether added with a saturated HCl solution in ether till acid pH The hydrochloride was recrystallized from isopropanol