5-己腈

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Through a stirred solution of 5-hexenenitrile (3 g, 31Mmol) and MeOH (35 mmol) in Et2O (30 ml), at 0° C., HCl gas was bubbled for 10 minutes. Solvent was evaporated in vacuo and the residue treated with Et2O to give 5.1 g of the title compound as white solid, which was used without further purification. Solvent was evaporated in vacuo the residue treated with Et2O

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Through a stirred solution of 5-hexenenitrile (3 g, 31Mmol) and MeOH (35 mmol) in Et2O (30 ml), at 0° C., HCl gas was bubbled for 10 minutes. Solvent was evaporated in vacuo and the residue treated with Et2O to give 5.1 g of the title compound as white solid, which was used without further purification. Solvent was evaporated in vacuo the residue treated with Et2O

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The reaction of epsilon-caprolactone with ammonia in the gas phase over alumina gives 22% of hex-1-ene-6-nitrile and 24% of epsilon-hydroxycapronitrile.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Through a stirred solution of 5-hexenenitrile (3 g, 31Mmol) and MeOH (35 mmol) in Et2O (30 ml), at 0° C., HCl gas was bubbled for 10 minutes. Solvent was evaporated in vacuo and the residue treated with Et2O to give 5.1 g of the title compound as white solid, which was used without further purification. Solvent was evaporated in vacuo the residue treated with Et2O