2-乙酰基-1-茚酮

反应条件: temp:52.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Acetyl-1-indanone (15 g, cf. Liebigs Ann. Chem. 347 (1906) 112) was added into a mixture of potassium carbonate (8.5 g) and dry N,N-dimethylformamide (45 ml). The mixture was stirred at 50-55° C. for 20 minutes and ethyl 3-bromopropionate (19 g) was then added and the stirring was continued at 50-55° C. for 6 hours. Water (60 ml) was added to the reaction mixture and the pH of the solution was adjusted to 2-3 with hydrochloric acid. The mixture was stirred at 50-55° C. for one hour. The cooled solution was extracted with toluene, washed with water, dried with sodium sulfate, and the solvent removed under reduced pressure. The yield was 23.5 g. the stirring was continued at 50-55° C. for 6 hours The mixture was stirred at 50-55° C. for one hour The cooled solution was extracted with toluene washed with water dried with sodium sulfate the solvent removed under reduced pressure

反应条件: temp:52.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Acetyl-1-indanone (15 g, cf. Liebigs Ann. Chem. 347 (1906) 112) was added into a mixture of potassium carbonate (8.5 g) and dry N,N-dimethylformamide (45 ml). The mixture was stirred at 50-55° C. for 20 minutes and ethyl 3-bromopropionate (19 g) was then added and the stirring was continued at 50-55° C. for 6 hours. Water (60 ml) was added to the reaction mixture and the pH of the solution was adjusted to 2-3 with hydrochloric acid. The mixture was stirred at 50-55° C. for one hour. The cooled solution was extracted with toluene, washed with water, dried with sodium sulfate, and the solvent removed under reduced pressure. The yield was 23.5 g. the stirring was continued at 50-55° C. for 6 hours The mixture was stirred at 50-55° C. for one hour The cooled solution was extracted with toluene washed with water dried with sodium sulfate the solvent removed under reduced pressure

反应条件: temp:52.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Acetyl-1-indanone (15 g, cf. Liebigs Ann. Chem. 347 (1906) 112) was added into a mixture of potassium carbonate (8.5 g) and dry N,N-dimethylformamide (45 ml). The mixture was stirred at 50-55° C. for 20 minutes and ethyl 3-bromopropionate (19 g) was then added and the stirring was continued at 50-55° C. for 6 hours. Water (60 ml) was added to the reaction mixture and the pH of the solution was adjusted to 2-3 with hydrochloric acid. The mixture was stirred at 50-55° C. for one hour. The cooled solution was extracted with toluene, washed with water, dried with sodium sulfate, and the solvent removed under reduced pressure. The yield was 23.5 g. the stirring was continued at 50-55° C. for 6 hours The mixture was stirred at 50-55° C. for one hour The cooled solution was extracted with toluene washed with water dried with sodium sulfate the solvent removed under reduced pressure

反应条件: temp:52.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Acetyl-1-indanone (15 g, cf. Liebigs Ann. Chem. 347 (1906) 112) was added into a mixture of potassium carbonate (8.5 g) and dry N,N-dimethylformamide (45 ml). The mixture was stirred at 50-55° C. for 20 minutes and ethyl 3-bromopropionate (19 g) was then added and the stirring was continued at 50-55° C. for 6 hours. Water (60 ml) was added to the reaction mixture and the pH of the solution was adjusted to 2-3 with hydrochloric acid. The mixture was stirred at 50-55° C. for one hour. The cooled solution was extracted with toluene, washed with water, dried with sodium sulfate, and the solvent removed under reduced pressure. The yield was 23.5 g. the stirring was continued at 50-55° C. for 6 hours The mixture was stirred at 50-55° C. for one hour The cooled solution was extracted with toluene washed with water dried with sodium sulfate the solvent removed under reduced pressure