反应 #1245914
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openreactiondata ↗doi:10.6084/m9.figshare.5104873.v1; patent:US09403808B2
反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to Example 69, using 5-cyclopropyl-6-cyclopropylmethoxy-pyrazine-2-carboxylic acid (Example 10 g, 50 mg, 0.214 mmol) and (1-amino-cyclohexyl)-methanol hydrochloride (CAN 5460-68-4, 22.8 mg, 0.17 mmol) as starting materials and isolated (46 mg, 62.32%) as white solid; LC-MS (UV peak area, ESI) 96.49%, 346.0 (M+H)+. isolated (46 mg, 62.32%) as white solid
来源 ID: ord-65c876e4bbd946b49d1006bcee6657c5