N-Methyl-4'-hydroxyacetoanilide

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In a similar manner to Example 9, a mixture of 4-amino-5-(4-iodophenyl)-7-(tert-butyl)pyrrolo[2,3-d]pyrimidine (100 mg), potassium carbonate (104 mg), N-methyl-(4-acetamido)phenol (120 mg), 8-hydroxyquinoline (8 mg), copper (I) chloride (5 mg) and dimethylacetamide (8 ml) gave N-{4-[4-(4-amino-7-tert-butylpyrrolo[2,3-d]-pyrimidin-5-yl)phenoxy]phenyl}-N-methylacetamide. This structure was confirmed by 1H nmr.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: In a similar manner to Example 9, a mixture of 4-amino-5-(4-iodophenyl)-7-(tert-butyl)pyrrolo[2,3-d]pyrimidine (100 mg), potassium carbonate (104 mg), N-methyl-(4-acetamido)phenol (120 mg), 8-hydroxyquinoline (8 mg), copper (I) chloride (5 mg) and dimethylacetamide (8 ml) gave N-{4-[4-(4-amino-7-tert-butylpyrrolo[2,3-d]-pyrimidin-5-yl)phenoxy]phenyl}-N-methylacetamide. This structure was confirmed by 1H nmr.