2-甲基-1-苯基-2-苯基硫基丙-1-one

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 68 g of 2-phenylthio-2-methylpropiophenone (1a) are added at 0° C. to a solution prepared from 500 ml of glacial acetic acid, 47 g of acetic anhydride and 45.5 g of 33% hydrogen peroxide. After 48 hours of agitation at ambient temperature, it is taken up in ethyl ether, washed with water and neutralised with sodium bicarbonate. washed with water and neutralised with sodium bicarbonate

反应条件: temp:2.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 10.88 g of a 50% suspension of sodium hydride in paraffin mineral oil are fed into 100 ml of DMF, followed slowly by 25.11 g of thiophenol. When dissolution is complete (65° C.), the solution is cooled to 2° C. and 36.5 g of 2-chloro-2-methylpropiophenone are fed in over 30 minutes maintaining the temperature below 10° C. When dissolution (65° C.) are fed in over 30 minutes maintaining the temperature below 10° C.