5-氟-2-甲基-1-苯并呋喃

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: According to the procedure of W. K. Anderson, et al., J. Chem. Soc., Perkin, 1, 1 (1976), a mixture of 2-(2-chloro-1-propen-3-yl)-4-fluorophenol (20.9 g, 0.112 mol) and concentrated hydrochloric acid (114 mL) was heated at 85°-89° C. for 24 hours. The mixture was cooled and diluted with ether. The ethereal layer was separated and washed with H2O, 5% KOH, and H2O, dried (MgSO4), and concentrated to give 12.40 g (74%) of product as a brown oil. was heated at 85°-89° C. for 24 hours The mixture was cooled The ethereal layer was separated washed with H2O, 5% KOH, and H2O dried (MgSO4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: According to the procedure of W. K. Anderson, et al., J. Chem. Soc., Perkin, 1, 1 (1976), a mixture of 2-(2-chloro-1-propen-3-yl)-4-fluorophenol (20.9 g, 0.112 mol) and concentrated hydrochloric acid (114 mL) was heated at 85°-89° C. for 24 hours. The mixture was cooled and diluted with ether. The ethereal layer was separated and washed with H2O, 5% KOH, and H2O, dried (MgSO4), and concentrated to give 12.40 g (74%) of product as a brown oil. was heated at 85°-89° C. for 24 hours The mixture was cooled The ethereal layer was separated washed with H2O, 5% KOH, and H2O dried (MgSO4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: According to the procedure of W. K. Anderson, et al., J. Chem. Soc., Perkin, 1, 1 (1976), a mixture of 2-(2-chloro-1-propen-3-yl)-4-fluorophenol (20.9 g, 0.112 mol) and concentrated hydrochloric acid (114 mL) was heated at 85°-89° C. for 24 hours. The mixture was cooled and diluted with ether. The ethereal layer was separated and washed with H2O, 5% KOH, and H2O, dried (MgSO4), and concentrated to give 12.40 g (74%) of product as a brown oil. was heated at 85°-89° C. for 24 hours The mixture was cooled The ethereal layer was separated washed with H2O, 5% KOH, and H2O dried (MgSO4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: According to the procedure of W. K. Anderson, et al., J. Chem. Soc., Perkin, 1, 1 (1976), a mixture of 2-(2-chloro-1-propen-3-yl)-4-fluorophenol (20.9 g, 0.112 mol) and concentrated hydrochloric acid (114 mL) was heated at 85°-89° C. for 24 hours. The mixture was cooled and diluted with ether. The ethereal layer was separated and washed with H2O, 5% KOH, and H2O, dried (MgSO4), and concentrated to give 12.40 g (74%) of product as a brown oil. was heated at 85°-89° C. for 24 hours The mixture was cooled The ethereal layer was separated washed with H2O, 5% KOH, and H2O dried (MgSO4) concentrated