1-(4-氯苯基)-3,3-二甲基丁烷-1-酮

反应条件: temp:140.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 18.5 g (0.2 mol) of sodium hydrogen sulphide (NaSH·H2O) in 100 ml of N-methylpyrrolidone are introduced and the water is removed by partial distillation with xylene. The mixture is cooled to 140° C., 21.05 g (0.1 mol) of 4-(neopentylcarbonyl)-chlorobenzene are added, and the mixture is further reacted at 160° C. for 3 hours and worked up as described in Example I-1 to give 14 g (70% of theory) of the desired product of boiling point: 110°-115° C./0.1 mbar. the water is removed by partial distillation with xylene the mixture is further reacted at 160° C. for 3 hours