反应 #3732790
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openreactiondata ↗doi:10.6084/m9.figshare.5104873.v1; patent:US06602861B1
反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The preparation of D-AC2 was identical to L-AC2 except D-glycerolphosphocholine, which was obtained from Synthetische Phosphor-Lipide, Biochemisches Labor, Bern CH Switzerland was used. L-PE2 was prepared by reacting glycerolphosphatidylethanolamine (L-α-GPE) with N-(9-Fluorenylmethoxycarbonyloxy) succinimide (FMOC-succinimide) to form L-α-GPE-FMOC followed by diacylation with 12MO anhydride then deprotection of FMOC with piperidine. L-PE1 was prepared by diacylating L-α-GPE-FMOC with myristic anhydride, then PLA2 cleavage to remove the sn-2 chain, then acylation with 12MO anhydride, and finally deprotection with piperidine to remove FMOC. to form L-α-GPE-FMOC L-PE1 was prepared PLA2 cleavage to remove the sn-2 chain acylation with 12MO anhydride, and finally deprotection with piperidine to remove FMOC
来源 ID: ord-a7bc296fd0c844d3859005778e3cf44e