2-氧代戊酸甲酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 0.916 g (7.035 mmol) of methyl 2-oxopentanoate in 15 ml of ethanol were initially introduced and heated to reflux. Then, 2.000 g (7.035 mmol) of 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidine-3-carboximidohydrazide suspended in 20 ml of ethanol were added and the mixture was heated under reflux overnight. After cooling, the mixture was filtered off with suction, and the filtercake was washed with a little ethanol and dried under high vacuum. This gave 1.75 g of the target compound (purity 92%; 63% of theory). heated to reflux were added the mixture was heated under reflux overnight After cooling the mixture was filtered off with suction the filtercake was washed with a little ethanol dried under high vacuum