1-(吡咯烷-2-基)乙-1-醇

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 1-pyrrolidin-2-yl-ethanol. The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid. The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 1-pyrrolidin-2-yl-ethanol. The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid. The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 1-pyrrolidin-2-yl-ethanol. The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid. The entitled compound was obtained as a pale yellow solid, diastereomer mixture, in the same method as in Example 15 or in accordance with the method The resulting diastereomer mixture was purified through partitioning thin-layer chromatography (Kieselgel™ 60F254, Art 5744 (by Merck), chloroform/methanol=10/1) into the individual diastereomers A and B each as a pale yellow solid