(2S)-2-氨基-N-甲基-4-甲基硫基丁酰胺

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: There were added to 40.0 grams (247 mmoles) of (S)-methionine mono-methylamide dissolved in 100 ml of n-pentane 27.5 ml (250 mmoles) of pivalaldehyde. The reaction mixture was boiled on the water separator until the formation of water ended (3 hours). The solvent was removed under reduced pressure and there remained behind 52.2 grams (92% of theory) of (S)-N-(2', 2'- dimethylpropylidene)-methionine mono-methylamide which was further processed without further purification. (3 hours) The solvent was removed under reduced pressure was further processed without further purification