(3E)-3-己烯-1,6-二醇

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 4-Methylmorpholine 4-oxide (50%) in water) was slowly added to a mixture of hex-3-ene-1,6-diol (7.2 g), acetone (77 ml), water (150 ml), tert-butanol (77 ml), methanesulfonamide (5.9 g) and potassium osmate (228 mg). After 12 hours, the mixture was concentrated and purified by column chromatography on silica gel (mobile phase: ethyl acetate/methanol 3:1). The product with a molecular weight of 150.18 (C6H14O4) was obtained in this way; MS (ESI): 151 (M+H+). the mixture was concentrated purified by column chromatography on silica gel (mobile phase: ethyl acetate/methanol 3:1) The product with a molecular weight of 150.18 (C6H14O4) was obtained in this way