6-脱氧-L-塔罗糖

反应条件: temp:78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The resin-supported molybdate obtained above (10 g) was added to a mixture of 6-deoxy-L-talose (10 g) in water (40 ml). The reaction mixture was stirred at 78° C. (inside the reactor). After cooling to rt the mixture was filtered, the filtrate passed through a column of IRA 400 resin (5 g, OH form, d=1 cm, l=5 cm) two times and concentrated. The residue was dissolved in isopropanol (40 ml) and directly evaporated. Isobutanol (50 ml) was added and the mixture was heated to reflux for 10 min. and allowed to cool. Crystallization spontaneously occurs or it was promoted by adding seed crystals. After 6 h at room temperature the suspension was filtered to give L-fucose (5.4 g, 54%). After cooling to rt the mixture was filtered concentrated The residue was dissolved in isopropanol (40 ml) directly evaporated Isobutanol (50 ml) was added the mixture was heated to reflux for 10 min. to cool Crystallization by adding seed crystals After 6 h at room temperature the suspension was filtered

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: MoO3 (600 mg) was added to a mixture of 6-deoxy-L-talose (100 g) in water (1.5 l). The reaction mixture was stirred for 9.5 h at reflux. At 80° C. resin IRA-67 (SUPELCO, 50 g) was added and the mixture was stirred for further 30 min, filtered and distilled off. The residue was dissolved in isopropanol (400 ml) and directly evaporated. Isobutanol (400 ml) was then added and the mixture was heated under reflux for 10 min and allowed to cool. Crystallization spontaneously occurs or it was promoted by adding seed crystals. After one night at room temperature the suspension was filtered to give L-fucose (52 g, 52%). at reflux At 80° C. (SUPELCO, 50 g) was added the mixture was stirred for further 30 min filtered distilled off The residue was dissolved in isopropanol (400 ml) directly evaporated Isobutanol (400 ml) was then added the mixture was heated under reflux for 10 min to cool Crystallization by adding seed crystals After one night at room temperature the suspension was filtered