苯基 己酸甲酯

反应条件: temp:120.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 24 g (0.18 mole) of powdered aluminium trichloride were carefully added to 31 g (0.16 mole) of phenyl hexanoate and the mixture was slowly heated with occasional stirring to 120° C and was held there for 11/2 hours. The residue was ground into a powder and was poured into iced dilute hydrochloric acid with stirring. The mixture was extracted with ether and the ether extracts were washed with dilute sodium hydroxide solution, then with water, dried over magnesium sulfate and evaporated to dryness to obtain 14.2 of (1-(2'-hydroxyphenyl)-hexan-1one as a pale yellow oil. IR spectrum showed o-hydroxyphenylcarbonyl at 1650cm-1. the mixture was slowly heated 2 hours with stirring The mixture was extracted with ether the ether extracts were washed with dilute sodium hydroxide solution with water, dried over magnesium sulfate evaporated to dryness

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 30 ml (0.22 mole) of hexanoyl chloride were added dropwise over 30 minutes with stirring and cooling on an ice bath to a solution of 18.8 g (0.2 mole) of phenol in 80 ml of anhydrous pyridine and then the reaction mixture stood at room temperature for 3 hours and was poured into ice water. The mixture was extracted with ether and the ether extracts were washed with water, dilute hydrochloric acid and with water, dried over magnesium sulfate and evaporated to dryness to obtain 36.4 g of phenyl hexanoate as a yellow oil. The mixture was extracted with ether the ether extracts were washed with water, dilute hydrochloric acid and with water dried over magnesium sulfate evaporated to dryness

反应条件: temp:120.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 24 g (0.18 mole) of powdered aluminium trichloride were carefully added to 31 g (0.16 mole) of phenyl hexanoate and the mixture was slowly heated with occassional stirring to 120° C and was held there for 11/2 hours. The residue was ground into a powder and was poured into iced dilute hydrochloric acid with stirring. The mixture was extracted with ether and the ether extracts were washed with dilute sodium hydroxide solution, then with water, dried over magnesium sulfate and evaporated to dryness to obtain 14.2 g of (1-(2'-hydroxyphenyl)-hexan-1-one as a pale yellow oil. IR spectrum showed o-hydroxyphenylcarbonyl at 1650cm-1. the mixture was slowly heated 2 hours with stirring The mixture was extracted with ether the ether extracts were washed with dilute sodium hydroxide solution with water, dried over magnesium sulfate evaporated to dryness

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 30 ml (0.22 mole) of hexanoyl chloride were added dropwise over 30 minutes with stirring and cooling on an ice bath to a solution of 18.8 g (0.2 mole) of phenol in 80 ml of anhydrous pyridine and then the reaction mixture stood at room temperature for 3 hours and was poured into ice water. The mixture was extracted with ether and the ether extracts were washed with water, dilute hydrochloric acid and with water, dried over magnesium sulfate and evaporated to dryness to obtain 36.4 g of phenyl hexanoate as a yellow oil. The mixture was extracted with ether the ether extracts were washed with water, dilute hydrochloric acid and with water dried over magnesium sulfate evaporated to dryness