tert-butyl 2-oxoimidazolidine-1-carboxylate

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 6-2 (28.0 g, 98 mmol), Mg(ClO4)2 (4.3 g, 20 mmol), and CH3CN (400 mL) was heated at 50° C. for 3 hr. The cooled solution was diluted with CHCl3 and then washed with 1N HCl, sat. naHCO3, and brine, dried (Mg SO4), and concentrated. Flash chromatography (silica, 50% EtOAc/hexanes→EtOAc) gave 6-3 as a yellow solid. washed with 1N HCl sat. naHCO3, and brine, dried (Mg SO4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butyoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 6-2 (28.0 g, 98 mmol), Mg(ClO4)2 (4.3 g, 20 mmol), and CH3CN (400 mL) was heated at 50° C. for 3 hr. The cooled solution was diluted with CHCl3 and then washed with 1N HCl, sat. naHCO3, and brine, dried (Mg SO4), and concentrated. Flash chromatography (silica, 50% EtOAc/hexanes→EtOAc) gave 6-3 as a yellow solid. washed with 1N HCl sat. naHCO3, and brine, dried (Mg SO4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 6-2 (28.0 g, 98 mmol), Mg(CIO4)2 (4.3 g, 20 mmol), and CH3CN (400 mL) was heated at 50° C. for 3 hr. The cooled solution was diluted with CHCl3 and then washed with 1N HCl, sat. naHCO3, and brine, dried (Mg S4), and concentrated. Flash chromatography (silica, 50% EtOAc/hexanes→EtOAc) gave 6-3 as a yellow solid. washed with 1N HCl sat. naHCO3, and brine, dried (Mg S4) concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butyoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone. This product, a liquid, was prepared

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of 6-2 (28.0 g, 98 mmol), Mg(ClO4)2 (4.3 g, 20 mmol), and CH3CN (400 mL) was heated at 50° C. for 3 hr. The cooled solution was diluted with CHCl3 and then washed with 1N HCl, sat. naHCO3, and brine, dried (Mg SO4), and concentrated. Flash chromatography (silica, 50% EtOAc/hexanes→EtOAc) gave 6-3 as a yellow solid. washed with 1N HCl sat. naHCO3, and brine, dried (Mg SO4) concentrated