2-氧代环戊烷甲酸叔丁酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of acrolein (4.19 g; 74.83 mmoles—2.5 eq.) in 10 mL of anhydrous dichloromethane is poured, over 30 minutes, at −25° C., under argon and with slow stirring, into a solution of tert-butyl 2-oxo-cyclopentanecarboxylate (5.51 g; 29.93 mmoles) and catalyst Q (1.46 g; 2.99 mmoles—0.1 eq.) in 60 mL of anhydrous dichloromethane