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2-(氨甲基)-1,4-二氧六环（CAS 88277-83-2）的产品身份、结构标识及相关反应资料，供化学中间体检索、研发和采购评估使用。
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12 条反应 · 12 篇文献
反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Following the procedure for 4-(3-fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile, using 1,4-dioxan-2-ylmethylamine in place of 2-aminoethanol, the title compound was synthesized.
来源 ID: ord-441a3f924d4f47d0becf19590b6cfb6d反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Following the procedure for 4-(3-fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile, using 1,4-dioxan-2-ylmethylamine in place of 2-aminoethanol, the title compound was synthesized.
来源 ID: ord-441a3f924d4f47d0becf19590b6cfb6d反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-chloro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and (1R,2R)-2-aminocyclohexanol as R1R2NH, MS (ISP) 501.4 (M+H)+.
来源 ID: ord-7677928d7be9466eab4c3a36cba5cc17反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-chloro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 485.5 (M+H)+.
来源 ID: ord-1df8192974834111968a5eb183ff64a9反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-(trifluoromethoxy)phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 467.5 (M+H)+.
来源 ID: ord-f6a5ba4234b84af9be7dc724f55f2577反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to Example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(5-chloro-2-methoxy-4-methyl-phenyl)-ethanone (purchased from Oakwood) as compound of formula S, rac-1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and piperidine-1-ylamine as R1R2NH, MS (ISP) 462.2 (M+H)+.
来源 ID: ord-35626689a35c4dd09bc9fb92596f41a5反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-chloro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and (1R,2R)-2-aminocyclohexanol as R1R2NH, MS (ISP) 501.4 (M+H)+.
来源 ID: ord-7677928d7be9466eab4c3a36cba5cc17反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-chloro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 485.5 (M+H)+.
来源 ID: ord-1df8192974834111968a5eb183ff64a9反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-(trifluoromethoxy)phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and cyclohexylamine as R1R2NH, MS (ISP) 467.5 (M+H)+.
来源 ID: ord-f6a5ba4234b84af9be7dc724f55f2577反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to Example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-(5-chloro-2-methoxy-4-methyl-phenyl)-ethanone (purchased from Oakwood) as compound of formula S, rac-1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and piperidine-1-ylamine as R1R2NH, MS (ISP) 462.2 (M+H)+.
来源 ID: ord-35626689a35c4dd09bc9fb92596f41a5反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Following the procedure for 4-(3-fluorophenyl)-1-[(2-hydroxyethyl)amino]-6-methoxyisoquinoline-3-carbonitrile, using 1,4-dioxan-2-ylmethylamine in place of 2-aminoethanol, the title compound was synthesized.
来源 ID: ord-441a3f924d4f47d0becf19590b6cfb6d反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: The title compound was synthesized in analogy to example 7, using 3-oxo-butyric acid methyl ester as compound of formula R, 2-bromo-1-[2-chloro-5-(trifluoromethyl)-phenyl]-ethanone as compound of formula S, 1,4-dioxane-2-methanamine as R3—(CH2)m—NH2 and (1R,2R)-2-aminocyclohexanol as R1R2NH, MS (ISP) 501.4 (M+H)+.
来源 ID: ord-7677928d7be9466eab4c3a36cba5cc17PubChem References
以下资料来自该化合物的公开数据库参考记录。
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