(4-(2-甲氧基乙基)苯基)甲醇

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: [4-(2-Methoxyethyl)phenyl]methanol (415 mg) synthesized in Reference Example 42 was dissolved in carbon tetrachloride (8 mL), triphenylphosphine (720 mg) was added thereto, and the mixture was heated under reflux for 4 hr. The reaction mixture was concentrated under reduced pressure, the residue was dissolved in hexane, the insoluble material was filtered off, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel chromatography (elution solvent; hexane:ethyl acetate=20:1) to give the title compound (225 mg) as a colorless oil. the mixture was heated under reflux for 4 hr The reaction mixture was concentrated under reduced pressure the residue was dissolved in hexane the insoluble material was filtered off the filtrate was evaporated under reduced pressure The residue was purified by silica gel chromatography (elution solvent; hexane:ethyl acetate=20:1)

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: [4-(2-Methoxyethyl)phenyl]methanol (415 mg) synthesized in Reference Example 42 was dissolved in carbon tetrachloride (8 mL), triphenylphosphine (720 mg) was added thereto, and the mixture was heated under reflux for 4 hr. The reaction mixture was concentrated under reduced pressure, the residue was dissolved in hexane, the insoluble material was filtered off, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel chromatography (elution solvent; hexane:ethyl acetate=20:1) to give the title compound (225 mg) as a colorless oil. the mixture was heated under reflux for 4 hr The reaction mixture was concentrated under reduced pressure the residue was dissolved in hexane the insoluble material was filtered off the filtrate was evaporated under reduced pressure The residue was purified by silica gel chromatography (elution solvent; hexane:ethyl acetate=20:1)