1-乙酰基吡咯-2,5-二酮

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of maleimide (68 g; 700 mmol) in acetic anhydride (500 ml) is placed in a 1000 ml three-necked flask and the reaction mixture is then brought to reflux for 3 hours. After returning to 20° C., the reaction mixture is evaporated under reduced pressure, resulting in an oil, which is crystallized from ethyl acetate (100 ml). After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml), and drying under reduced pressure at constant weight, N-acetylmaleimide (64.1 g; 65.8%) is isolated, the characteristics of which are as follows: to reflux for 3 hours After returning to 20° C. the reaction mixture is evaporated under reduced pressure resulting in an oil, which is crystallized from ethyl acetate (100 ml) After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml) drying under reduced pressure at constant weight

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of maleimide (68 g; 700 mmol) in acetic anhydride (500 ml) is placed in a 1000 ml three-necked flask and the reaction mixture is then brought to reflux for 3 hours. After returning to 20° C., the reaction mixture is evaporated under reduced pressure, resulting in an oil, which is crystallized from ethyl acetate (100 ml). After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml), and drying under reduced pressure at constant weight, N-acetylmaleimide (64.1 g; 65.8%) is isolated, the characteristics of which are as follows: to reflux for 3 hours After returning to 20° C. the reaction mixture is evaporated under reduced pressure resulting in an oil, which is crystallized from ethyl acetate (100 ml) After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml) drying under reduced pressure at constant weight

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of maleimide (68 g; 700 mmol) in acetic anhydride (500 ml) is placed in a 1000 ml three-necked flask and the reaction mixture is then brought to reflux for 3 hours. After returning to 20° C., the reaction mixture is evaporated under reduced pressure, resulting in an oil, which is crystallized from ethyl acetate (100 ml). After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml), and drying under reduced pressure at constant weight, N-acetylmaleimide (64.1 g; 65.8%) is isolated, the characteristics of which are as follows: to reflux for 3 hours After returning to 20° C. the reaction mixture is evaporated under reduced pressure resulting in an oil, which is crystallized from ethyl acetate (100 ml) After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml) drying under reduced pressure at constant weight

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: A solution of maleimide (68 g; 700 mmol) in acetic anhydride (500 ml) is placed in a 1000 ml three-necked flask and the reaction mixture is then brought to reflux for 3 hours. After returning to 20° C., the reaction mixture is evaporated under reduced pressure, resulting in an oil, which is crystallized from ethyl acetate (100 ml). After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml), and drying under reduced pressure at constant weight, N-acetylmaleimide (64.1 g; 65.8%) is isolated, the characteristics of which are as follows: to reflux for 3 hours After returning to 20° C. the reaction mixture is evaporated under reduced pressure resulting in an oil, which is crystallized from ethyl acetate (100 ml) After filtering-off the solid and washing with ethyl acetate (25 ml) and diisopropyl ether (100 ml) drying under reduced pressure at constant weight