乙基(甲基)-2-乙氧基-四氢-3-糠酸酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (10 g, 62.5 mmol) in 60 ml of dry THF was added 4.75 g (125 mmol) LiAlH4 at 25° C. The mixture was refluxed for 4 hrs and cooled. 4.75 ml of H2O and 4.75 ml of aq. NaOH(10%) were added to the reaction mixture in turn. The resulting mixture was filtered and the filtrate was concentrated to yield (2-methoxy-tetrahydro-furan-3-yl)-methanol (7 g). The mixture was refluxed for 4 hrs cooled The resulting mixture was filtered the filtrate was concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (10 g, 62.5 mmol) in 60 ml of dry THF was added 4.75 g (125 mmol) LiAlH4 at 25° C. The mixture was refluxed for 4 hrs and cooled. 4.75 ml of H2O and 4.75 ml of aq. NaOH(10%) were added to the reaction mixture in turn. The resulting mixture was filtered and the filtrate was concentrated to yield (2-methoxy-tetrahydro-furan-3-yl)-methanol (7 g). The mixture was refluxed for 4 hrs cooled The resulting mixture was filtered the filtrate was concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (10 g, 62.5 mmol) in 60 ml of dry THF was added 4.75 g (125 mmol) LiAlH4 at 25° C. The mixture was refluxed for 4 hrs and cooled. 4.75 ml of H2O and 4.75 ml of aq. NaOH(10%) were added to the reaction mixture in turn. The resulting mixture was filtered and the filtrate was concentrated to yield (2-methoxy-tetrahydro-furan-3-yl)-methanol (7 g). The mixture was refluxed for 4 hrs cooled The resulting mixture was filtered the filtrate was concentrated

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 2-methoxy-tetrahydro-furan-3-carboxylic acid methyl ester (10 g, 62.5 mmol) in 60 ml of dry THF was added 4.75 g (125 mmol) LiAlH4 at 25° C. The mixture was refluxed for 4 hrs and cooled. 4.75 ml of H2O and 4.75 ml of aq. NaOH (10%) were added to the reaction mixture in turn. The resulting mixture was filtered and the filtrate was concentrated to yield (2-methoxy-tetrahydro-furan-3-yl)-methanol (7 g). The mixture was refluxed for 4 hrs cooled The resulting mixture was filtered the filtrate was concentrated