2-[(2-溴苯基)甲氧基]乙醇

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The reaction and work up was conducted as described in the preparation of compound 415. Starting materials were NaH (60% in oil, 1.8 g, 44 mmol) in THF (160 mL), ethylenglycol (13.4 mL, 240 mmol), 2-bromo-benzyl bromide (10 g, 40 mmol) dissolved in 5 mL dry THF and tetrabutylammonium iodide (0.15 g, 0.4 mmol). The crude product was purified by flash chromatography using DCM/Acetone 30:1 as the eluent to afford the title compound as a pale yellow oil. The reaction and work The crude product was purified by flash chromatography