二硫化四乙基秋兰姆

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Nocceler DM: dibenzothiazyl disulfide (vulcanization accelerator) manufactured by Ohuchi Shinko Kagaku Kogyo Co., Ltd.

反应条件: temp:60.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Diethylamine (150 g, 2.05 moles) and manganese acetate catalyst (30 mg, 0.12 mmole) were charged into a 1 liter reactor at room temperature. The reactor was evacuated to 0.6×105 Pa (0.6 bar) and carbon disulfide (87.5 g, 1.15 moles) was dosed in 20 min while increasing the temperature to 60° C. The reactor was pressurized to 3×105 (3 bar) with pure oxygen and the stirring speed was raised to 1400 rpm. Carbon disulfide dosing was started again at a dosing rate of 2 moles per mole oxygen reacted, i.e. 68.5 g (0.90 mole) in 280 min. The reaction was stopped when the oxygen flow fell below 1 ml/min. After removal of the reaction water formed by evaporation, 295 g of tetraethyl thiuram disulfide were obtained (yield: 97.2 wt %) with a purity of 96.7 wt % (as determine d by the H2S titration method). the stirring speed was raised to 1400 rpm reacted i.e. 68.5 g (0.90 mole) in 280 min After removal of the reaction water formed by evaporation

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Nocceler DM: dibenzothiazyl disulfide (vulcanization accelerator) manufactured by Ohuchi Shinko Kagaku Kogyo Co., Ltd.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Nocceler DM: dibenzothiazyl disulfide (vulcanization accelerator) manufactured by Ohuchi Shinko Kagaku Kogyo Co., Ltd.

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal supplied by the Department of Pharmaceutical Development at our Institute. [3H]-Thymidine was purchased from New England Nuclear, Boston, Mass. Concanavalin A, horse serum, RPMI-1640 and HEPES were from Gibco, Grand Island, N.Y. NAD and NADP were purchased from Boehringer, Mannheim. Acrolein and disulfiram were obtained from Aldrich Chemical Co., Milwaukee, Wis. Propionaldehyde and benzaldehyde were from Eastman Kodak Chemical Co., Rochester, N.Y. Diethyl aminobenzaldehyde (DEAB) was kindly provided by Dr. John Hilton, Johns Hopkins School of Medicine, Baltimore, Md. Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal

反应条件: temp:60.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Diethylamine (150 g, 2.05 moles) and manganese acetate catalyst (30 mg, 0.12 mmole) were charged into a 1 liter reactor at room temperature. The reactor was evacuated to 0.6×105 Pa (0.6 bar) and carbon disulfide (87.5 g, 1.15 moles) was dosed in 20 min while increasing the temperature to 60° C. The reactor was pressurized to 3×105 (3 bar) with pure oxygen and the stirring speed was raised to 1400 rpm. Carbon disulfide dosing was started again at a dosing rate of 2 moles per mole oxygen reacted, i.e. 68.5 g (0.90 mole) in 280 min. The reaction was stopped when the oxygen flow fell below 1 ml/min. After removal of the reaction water formed by evaporation, 295 g of tetraethyl thiuram disulfide were obtained (yield: 97.2 wt %) with a purity of 96.7 wt % (as determine d by the H2S titration method). the stirring speed was raised to 1400 rpm reacted i.e. 68.5 g (0.90 mole) in 280 min After removal of the reaction water formed by evaporation

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Nocceler DM: dibenzothiazyl disulfide (vulcanization accelerator) manufactured by Ohuchi Shinko Kagaku Kogyo Co., Ltd.