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甲基2-氧-2-(2-苯氧苯基)醋酸盐（CAS 103474-01-7）的产品身份、结构标识及相关反应资料，供化学中间体检索、研发和采购评估使用。
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12 条反应 · 10 篇文献
反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Some examples for production of methyl-2-(2-phenoxyphenyl)-2-oxo-acetate, which is the intermediate compound for methyl-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide, are as follows:
来源 ID: ord-e854342ab76147258db741259a4d86fa反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methahol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. nD23.3 1.5978. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-d828b7956e3840b88e5ceeda1d56b9de反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methahol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. nD23.3 1.5978. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-d828b7956e3840b88e5ceeda1d56b9de反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Some examples for production of methyl-2-(2-phenoxyphenyl)-2-oxo-acetate, which is the intermediate compound for methyl-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide, are as follows:
来源 ID: ord-429f988e2f7141d182e49c0bb5b60426反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methanol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. nD23.3 1.5978. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-73dd3491930742889e73b6177fe055a7反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methanol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-da1a2cca61f24cc6a09b91e7eb8ec3f7反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Some examples for production of methyl-2-(2-phenoxyphenyl)-2-oxo-acetate, which is the intermediate compound for methyl-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide, are as follows:
来源 ID: ord-dffa1fcd931a46f7a49b79ce3fc0d0d8反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methahol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. nD23.3 1.5978. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-6a434bf132e74eb991b4337c9ec8ccfc反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: Some examples for production of methyl-2-(2-phenoxyphenyl)-2-oxo-acetate, which is the intermediate compound for methyl-2-(2-phenoxyphenyl)-2-methoxyiminoacetamide, are as follows:
来源 ID: ord-e854342ab76147258db741259a4d86fa反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: To a solution of methyl-(2-phenoxyphenyl)-2-oxoacetate (0.70 g) in methanol (10 ml), 28% aqueous ammonium hydroxide (2.0 ml) was added, and the resultant mixture was stirred overnight, followed by removal of the solvent under reduced pressure. The residue was combined with diethyl ether (150 ml) and water (50 ml) under stirring and, upon dissolution, allowed to stand. The organic layer was separated, washed and dried over anhydrous sodium sulfate. Upon filtration, the filtrate was concentrated under reduced pressure to give residual yellow crystals, which were combined with methahol (10 ml) and O-methylhydroxylamine hydrochloride (1.49 g) while stirring and refluxed for 6 hours. Water (50 ml) was added to the reaction mixture, which was extracted with diethyl ether. The organic layer was washed with water and dried over anhydrous sodium sulfate, followed by filtration. The filtrate was concentrated under reduced pressure to give oily residue. The residue was purified by silica gel column chromatography with benzene to give 0.36 g of the objective compound. nD23.3 1.5978. followed by removal of the solvent under reduced pressure The organic layer was separated washed dried over anhydrous sodium sulfate Upon filtration the filtrate was concentrated under reduced pressure to give residual yellow crystals, which while stirring refluxed for 6 hours was extracted with diethyl ether The organic layer was washed with water dried over anhydrous sodium sulfate followed by filtration The filtrate was concentrated under reduced pressure to give oily residue The residue was purified by silica gel column chromatography with benzene
来源 ID: ord-d828b7956e3840b88e5ceeda1d56b9dePubChem References
以下资料来自该化合物的公开数据库参考记录。