(R)-(+)-1-BOC-4-哌啶酮-2-甲酸

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound (D63) (295 mg) was prepared according to the general procedure for amides preparation (Method C) starting from (R)-1-(tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid (200 mg) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (206 mg). Reaction time: 18 hrs Reaction time 18 hrs

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound (D63) (295 mg) was prepared according to the general procedure for amides preparation (Method C) starting from (R)-1-(tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid (200 mg) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (206 mg). Reaction time: 18 hrs Reaction time 18 hrs

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound (D60) (300 mg) was prepared according to the general procedure for amides preparation (Method C) starting from (R)-1-(tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid (200 mg; available from Aldrich#701130) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (195 mg). Reaction time: 1 h Reaction time 1 h

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound (D63) (295 mg) was prepared according to the general procedure for amides preparation (Method C) starting from (R)-1-(tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid (200 mg) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (206 mg). Reaction time: 18 hrs Reaction time 18 hrs

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The title compound (D60) (300 mg) was prepared according to the general procedure for amides preparation (Method C) starting from (R)-1-(tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid (200 mg; available from Aldrich#701130) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (195 mg). Reaction time: 1 h Reaction time 1 h