甲基糠基醚

反应条件: temp:-12.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Methoxymethyl furan (120.4 g, 1.07 moles), anhydrous methanol (250 ml, 6.18 moles), anhydrous sodium carbonate (190 g), and methylene chloride (250 ml) were placed in a 3L three-necked flask equipped with a mechanical stirrer and an addition funnel. The mixture was cooled to -10 to -15° C. and an ice-cold solution of bromine (53 ml, 1.04 moles) in 500 ml anhydrous methanol was added dropwise with stirring. Four hours after the addition of the bromine solution, the mixture was filtered by suction. The excess solvent was removed on a rotatory evaporator and the crude product was distilled under reduced pressure to give colorless 2-methoxymethyl-2,5-dimethoxy-2,5dihydrofuran (118.3 g, 65%), bp. 57°-58° C. (0.2 mm Hg), nD =1.4414. equipped with a mechanical stirrer and an addition funnel the mixture was filtered by suction The excess solvent was removed on a rotatory evaporator the crude product was distilled under reduced pressure

反应条件: temp:-12.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Methoxymethyl furan (120.4 g, 1.07 moles), anhydrous methanol (250 ml, 6.18 moles), anhydrous sodium carbonate (190 g), and methylene chloride (250 ml) were placed in a 3L three-necked flask equipped with a mechanical stirrer and an addition funnel. The mixture was cooled to -10 to -15° C. and an ice-cold solution of bromine (53 ml, 1.04 moles) in 500 ml anhydrous methanol was added dropwise with stirring. Four hours after the addition of the bromine solution, the mixture was filtered by suction. The excess solvent was removed on a rotatory evaporator and the crude product was distilled under reduced pressure to give colorless 2-methoxymethyl-2,5-dimethoxy-2,5dihydrofuran (118.3 g, 65%), bp. 57°-58° C. (0.2 mm Hg), nD =1.4414. equipped with a mechanical stirrer and an addition funnel the mixture was filtered by suction The excess solvent was removed on a rotatory evaporator the crude product was distilled under reduced pressure

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Methoxymethyl furan (120.4 g, 1.07 moles), anhydrous methanol (250 ml, 6.18 moles), anhydrous sodium carbonate (190 g), and methylene chloride (250 ml) were placed in a 3L three-necked flask equipped with a mechanical stirrer and an addition funnel. The mixture was cooled to -10° to -15° C. and an ice-cold solution of bromine (53 ml, 1.04 moles) in 500 ml anhydrous methanol was added dropwise with stirring. Four hours after the addition of the bromine solution, the mixture was filtered by suction. The excess solvent was removed on a rotatory evaporator and the crude product was distilled under reduced pressure to give colorless 2-methoxymethyl-2,5-dimethoxy-2,5-dihydrofuran (118.3 g, 65%), bp. 57°-58° C. (0.2 mm Hg), n21 -1.4414. equipped with a mechanical stirrer and an addition funnel The mixture was cooled to -10° to -15° C. the mixture was filtered by suction The excess solvent was removed on a rotatory evaporator the crude product was distilled under reduced pressure

反应条件: temp:-12.51; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: 2-Methoxymethyl furan (120.4 g, 1.07 moles), anhydrous methanol (250 ml, 6.18 moles), anhydrous sodium carbonate (190 g), and methylene chloride (250 ml) were placed in a 3L three-necked flask equipped with a mechanical stirrer and an addition funnel. The mixture was cooled to -10 to -15° C. and an ice-cold solution of bromine (53 ml, 1.04 moles) in 500 ml anhydrous methanol was added dropwise with stirring. Four hours after the addition of the bromine solution, the mixture was filtered by suction. The excess solvent was removed on a rotatory evaporator and the crude product was distilled under reduced pressure to give colorless 2-methoxymethyl-2,5-dimethoxy-2,5dihydrofuran (118.3 g, 65%), bp. 57°-58° C. (0.2 mm Hg), nD =1.4414. equipped with a mechanical stirrer and an addition funnel the mixture was filtered by suction The excess solvent was removed on a rotatory evaporator the crude product was distilled under reduced pressure