甲基 1-(氧杂-4-基)氮杂环丁烷-2-羧酸乙酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: The reaction of methyl 2,4-dibromobutanoate 17 with 4-aminotetrahydropyran 18E yielded 1-(tetrahydro-pyran-4-yl)-azetidine-2-carboxylic acid methyl ester as a light yellow oil (27%). MS ISP (m/e): 200.2 (100) [(M+H)]+.