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CCOC(=O)C(C)OC1=C(C=CC=C1Cl)Cl产品信息
乙基2-(2,6-二氯苯氧基)丙酸酯（CAS 344559-34-8）的产品身份、结构标识及相关反应资料，供化学中间体检索、研发和采购评估使用。
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合成路线数据
12 条反应 · 12 篇文献
反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-bed409b366e0437a8ac7eccfbaf8fd26反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-2560c2b29a5a47ceab7dd6c7ccad59a7反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-dfe682a2894245779d36a8656bcb2cdc反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: 42.0 g (=0.160 mols) of (+)-2-(2,6-dichlorophenoxy)-propionic acid ethylester are stirred for 6 hours at room temperature with 194.0 g (=3.228 mols) of 1,2-diaminoethane and, after working up, produce 34.0 g of (+)-2-(2,6-dichlorophenoxy)-propionic acid-N-(2-aminoethyl)amide, C11H14Cl2N2O2 [277.2] as a high viscosity oil, [α]D20 =+5.6° (c=1/ethanol).
来源 ID: ord-3a08fc7097a44d909070b63b9c8caf22反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: 46.0 g (0.1748 mols) of (-)-2-(2,6-dichlorophenoxy)-propionic acid ethylester are stirred for 6 hours at room temperature with 212.0 g (3.527 mols) of 1,2-diaminoethane and, after working up, produce 38.0 g (-)-2-(2,6-dichlorophenoxy)-propionic acid-N-(2-aminoethyl)-amide, C11H14Cl2N2O2 [277.2] as a high viscosity oil, [α]D20 =-5.8° (c=1/ethanol)
来源 ID: ord-4e85bf5d297f41329ef4c9b741b894bb反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: 46.0 g (0.1748 mols) of (-)-2-(2,6-dichlorophenoxy)-propionic acid ethylester are stirred for 6 hours at room temperature with 212.0 g (3.527 mols) of 1,2-diaminoethane and, after working up, produce 38.0 g (-)-2-(2,6-dichlorophenoxy)-propionic acid-N-(2-aminoethyl)-amide, C11H14Cl2N2O2 [277.2] as a high viscosity oil, [α]D20 =-5.8° (c=1/ethanol)
来源 ID: ord-4e85bf5d297f41329ef4c9b741b894bb反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: In a variation of the present process, the (-)-2-(2,6-dichlorophenoxy)-propionic acid ethylester obtained as above described, is reacted with an ethanolic solution of ammonia at room temperature and is converted into (+)-2-(2,6-dichlorophenoxy)-propionic acid amide which is difficultly soluble in ethanol. This amide is dehydrated at from 0° to 30° C. with a titanium tetrachloride/tetrahydrofurane complex and 4-methyl-morpholine in chloroform into (-)-2-(2,6-dichlorophenoxy)-propionic acid nitrile. By introducing hydrogen chloride at 0° C., the nitrile is then converted with ethanol in chloroform into (-)-2-(2,6-dichlorophenoxy)-propionimido acid ethylester hydrochloride. This compound is dissolved in ethanol and is cyclized by adding 1,2-diaminoethane to produce (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene. Analogously to the previous process, (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride is produced from the (-)-base thus obtained.
来源 ID: ord-f2b5c06e54344ce2a3160672364e9fcb反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: 42.0 g (=0.160 mols) of (+)-2-(2,6-dichlorophenoxy)-propionic acid ethylester are stirred for 6 hours at room temperature with 194.0 g (=3.228 mols) of 1,2-diaminoethane and, after working up, produce 34.0 g of (+)-2-(2,6-dichlorophenoxy)-propionic acid-N-(2-aminoethyl)amide, C11H14Cl2N2O2 [277.2] as a high viscosity oil, [α]D20 =+5.6° (c=1/ethanol).
来源 ID: ord-3a08fc7097a44d909070b63b9c8caf22反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
实验步骤: 42.0 g (=0.160 mols) of (+)-2-(2,6-dichlorophenoxy)-propionic acid ethylester are stirred for 6 hours at room temperature with 194.0 g (=3.228 mols) of 1,2-diaminoethane and, after working up, produce 34.0 g of (+)-2-(2,6-dichlorophenoxy)-propionic acid-N-(2-aminoethyl)amide, C11H14Cl2N2O2 [277.2] as a high viscosity oil, [α]D20 =+5.6° (c=1/ethanol).
来源 ID: ord-3a08fc7097a44d909070b63b9c8caf22反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-bed409b366e0437a8ac7eccfbaf8fd26反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-2560c2b29a5a47ceab7dd6c7ccad59a7反应条件: temp:0.00; pressure:0.00; stir:
来源 ID: ord-dfe682a2894245779d36a8656bcb2cdcPubChem References
以下资料来自该化合物的公开数据库参考记录。