2,3-呋喃二甲酸二甲酯

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Furan-2,3-dicarboxylic acid dimethyl ester (1.6 g, 8.69 mmol) is added to EtOH (10 mL) and hydrazine hydrate (1.46 mL, 55% in water). Heat the reaction to reflux for 5-6 h. Cool and concentrate in vacuo to form a slurry. Dilute the material with additional H2O and filter the precipitate. Wash with additional H2O. Transfer material from filter to a round bottom flask and add HCl (7.2 mL, 2N in H2O). Heat reaction mixture to reflux for 4 h. Cool and filter the precipitate washing with H2O, to yield the title compound without further purification (930 mg, 70%) Heat the reaction to reflux for 5-6 h Cool concentrate in vacuo to form a slurry filter the precipitate Wash with additional H2O Transfer material from filter to a round bottom flask add HCl (7.2 mL, 2N in H2O) Heat reaction mixture to reflux for 4 h Cool filter the precipitate washing with H2O

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Furan-2,3-dicarboxylic acid dimethyl ester (1.6 g, 8.69 mmol) is added to EtOH (10 mL) and hydrazine hydrate (1.46 mL, 55% in water). Heat the reaction to reflux for 5-6 h. Cool and concentrate in vacuo to form a slurry. Dilute the material with additional H2O and filter the precipitate. Wash with additional H2O. Transfer material from filter to a round bottom flask and add HCl (7.2 mL, 2N in H2O). Heat reaction mixture to reflux for 4 h. Cool and filter the precipitate washing with H2O, to yield the title compound without further purification (930 mg, 70%) Heat the reaction to reflux for 5-6 h Cool concentrate in vacuo to form a slurry filter the precipitate Wash with additional H2O Transfer material from filter to a round bottom flask add HCl (7.2 mL, 2N in H2O) Heat reaction mixture to reflux for 4 h Cool filter the precipitate washing with H2O

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: Furan-2,3-dicarboxylic acid dimethyl ester (1.6 g, 8.69 mmol) is added to EtOH (10 mL) and hydrazine hydrate (1.46 mL, 55% in water). Heat the reaction to reflux for 5-6 h. Cool and concentrate in vacuo to form a slurry. Dilute the material with additional H2O and filter the precipitate. Wash with additional H2O. Transfer material from filter to a round bottom flask and add HCl (7.2 mL, 2N in H2O). Heat reaction mixture to reflux for 4 h. Cool and filter the precipitate washing with H2O, to yield the title compound without further purification (930 mg, 70%) Heat the reaction to reflux for 5-6 h Cool concentrate in vacuo to form a slurry filter the precipitate Wash with additional H2O Transfer material from filter to a round bottom flask add HCl (7.2 mL, 2N in H2O) Heat reaction mixture to reflux for 4 h Cool filter the precipitate washing with H2O