1-氯-1-亚硝基环己烷

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 1-chloro-1-nitrosocyclohexane (3.22 g, 21.86 mmol) in ethanol (2.31 ml) and diethyl ether (8 ml) cooled in an ice bath was added a solution of 1-(4-ethoxyphenyl)-2-methylpent-1E,3E-diene (4.0 g, 19.88 mmol) in diethyl ether (4 ml). The reaction vessel was sealed and kept in a fridge at 0° C. over a period of 4 weeks yielding three crops of 3,6-dihydro-3,5-dimethyl-6-(4-ethoxyphenyl)-2H-1,2-oxazine hydrochloride as white crystals. The reaction vessel was sealed kept in a fridge at 0° C. over a period of 4 weeks

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 6.1 g of 1-chloro-1-nitrosocyclohexane in 135 ml of ethanol and 260 ml of carbon tetrachloride, cooled to -20° C. in an acetone-dry ice bath, was slowly added 33.6 ml of 1,3-cyclohexadiene. The mixture was stored at -20° C. for 6 days and the solid collected, giving 4.5 g of 2-oxa-3-azabicyclo[2.2.2]oct-5-ene, hydrochloride. the solid collected

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 6.1 g of 1-chloro-1-nitrosocyclohexane in 135 ml of ethanol and 260 ml of carbon tetrachloride, cooled to -20° C. in an acetone-dry ice bath, was slowly added 33.6 ml of 1,3-cyclohexadiene. The mixture was stored at -20° C. for 6 days and the solid collected, giving 4.5 g of 2-oxa-3-azabicyclo[2.2.2]oct-5-ene, hydrochloride. the solid collected

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 1-chloro-1-nitrosocyclohexane (3.22 g, 21.86 mmol) in ethanol (2.31 ml) and diethyl ether (8 ml) cooled in an ice bath was added a solution of 1-(4-ethoxyphenyl)-2-methylpent-1E,3E-diene (4.0 g, 19.88 mmol) in diethyl ether (4 ml). The reaction vessel was sealed and kept in a fridge at 0° C. over a period of 4 weeks yielding three crops of 3,6-dihydro-3,5-dimethyl-6-(4-ethoxyphenyl)-2H-1,2-oxazine hydrochloride as white crystals. The reaction vessel was sealed kept in a fridge at 0° C. over a period of 4 weeks

反应条件: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

实验步骤: To a solution of 6.1 g of 1-chloro-1-nitrosocyclohexane in 135 ml of ethanol and 260 ml of carbon tetrachloride, cooled to -20° C. in an acetone-dry ice bath, was slowly added 33.6 ml of 1,3-cyclohexadiene. The mixture was stored at -20° C. for 6 days and the solid collected, giving 4.5 g of 2-oxa-3-azabicyclo[2.2.2]oct-5-ene, hydrochloride. the solid collected